【摘要】 目的 比较麻醉药物和血管扩张药应用于急性颅脑外伤手术中进行控制性降压的效果。方法 121例因脑外伤行手术的病人随机分为两组，Ⅰ组病人(60例)以硝普钠进行控制性降压，Ⅱ组病人(61例)调节麻醉用药进行控制性降压，观察麻醉前、降压15min、降压45min及降压后30min患者心率(HR)和平均动脉压(MAP)及血压波动情况，在开颅前(t 1 )、关颅前(t 2 )分别测定颅内压及进行脑肿胀程度评分，记录术中出血量。结果 两组病人降压后平均动脉压较麻醉前均出现明显下降，同一时间点两组间比较差异无显著性(P>0.05)。两组病人t 1 时颅内压明显低于t 2 时(P<0.05)。Ⅱ组病人降压过程中血压升高次数明显多于I组(P<0.05)。结论 应用硝普钠降压于脑外伤手术中，安全、有效且易于保持降压平稳。

    关键词 控制性降压 脑外伤 手术 全身麻醉

    Application of deliberate hypotensive on the patients surgical treatment of acute brain injure

    Luo Qing

    The Department of Anesthesiology，The People’s Hospital，Sanshui528100.

    【Abstract】 Objective To compare the effect of Deliberate Hypotensive of anesthetic and vasodilator what were used in the patient surgical treatment of acute brain injure. Methods One hundred and twenty on patients of acute brain injure who needed surgical treatment were randomly divided into groupⅠandⅡ. GroupⅠsixty patients were given to deliberate hypotension ......