美国婴儿脑损伤发病率约30/10万[英文]
http://www.100md.com
Approximately 30 per 100,000 infants experience a serious or fatal inflicted brain injury in the United States, according to a prospective, population-based analysis of traumatic brain injury (TBI) in young children who were treated in 9 hospitals in North Carolina.
Heather T. Keenan, MDCM, MPH, of the University of North Carolina at Chapel Hill, United States, and colleagues identified 152 North Carolina resident children, 2 years old or younger, who experienced a serious or fatal TBI between January 1, 2000 and December 31, 2001, and who were treated at a paediatric intensive care unit or a monitored step-down unit. Among the 152 children 57% were boys and 78% were infants (12 months old or younger).
Overall, 53% of the brain injury cases were inflicted with fatalities occurring in 18 of these cases. The incidence of inflicted TBI during the first 2 years of life was 17.0 per 100,000 person-years. Among infants, the incidence of inflicted TBI was 29.7 per 100,000 person-years, while children aged from 1 to 2 years had an inflicted TBI incidence of 3.8 per 100,000 person-years.
The inflicted TBI incidence was higher in boys than in girls (21.0 versus 13.0 per 100,000 person-years). Compared with the general population, children born to mothers 21 years old or younger, or were products of multiple births, or were of non-European American origin had an increased risk of incurring inflicted TBI.
The authors note that this study included only those children who were treated in a pediatric intensive care or a monitored step-down unit. Because many children may not present for medical care after undergoing an initial episode of inflicted TBI, Dr. Keenan and colleagues conclude, "Our estimate is a lower-bound estimate of the overall problem of inflicted TBI."
JAMA 2003;290:621-626., http://www.100md.com
Heather T. Keenan, MDCM, MPH, of the University of North Carolina at Chapel Hill, United States, and colleagues identified 152 North Carolina resident children, 2 years old or younger, who experienced a serious or fatal TBI between January 1, 2000 and December 31, 2001, and who were treated at a paediatric intensive care unit or a monitored step-down unit. Among the 152 children 57% were boys and 78% were infants (12 months old or younger).
Overall, 53% of the brain injury cases were inflicted with fatalities occurring in 18 of these cases. The incidence of inflicted TBI during the first 2 years of life was 17.0 per 100,000 person-years. Among infants, the incidence of inflicted TBI was 29.7 per 100,000 person-years, while children aged from 1 to 2 years had an inflicted TBI incidence of 3.8 per 100,000 person-years.
The inflicted TBI incidence was higher in boys than in girls (21.0 versus 13.0 per 100,000 person-years). Compared with the general population, children born to mothers 21 years old or younger, or were products of multiple births, or were of non-European American origin had an increased risk of incurring inflicted TBI.
The authors note that this study included only those children who were treated in a pediatric intensive care or a monitored step-down unit. Because many children may not present for medical care after undergoing an initial episode of inflicted TBI, Dr. Keenan and colleagues conclude, "Our estimate is a lower-bound estimate of the overall problem of inflicted TBI."
JAMA 2003;290:621-626., http://www.100md.com