【摘要】 目的 探讨应用磷酸铬 32 CrPO 4 -超液碘化油( 32 P胶体-LUP)混悬液经肝动脉超选择栓塞介入治疗肝癌的方法和疗效。 方法 采用Slendinger方法，经股动脉超插至肿瘤供血动脉，注入 32 P胶体-LUP混悬液和化疗药介入治疗中晚期肝癌，单次剂量1:1。 结果 30例(观察组)接受 32 P胶体-LUP混悬液介入栓塞治疗，对肝功能Child B级也可采用，肝功能损害不大。Child A级者其6、12、18个月生存率为85.7%、64.1%和42.8%，较常规剂量对照组高(P=0.0059<0.01)，Child B级者其6、12、18个月生存率也有提高，分别为56.2%、31.3%、6.25%。 结论 32 P胶体-LUP混悬液超选择肝动脉栓塞介入治疗肝癌，疗效优于常规剂量介入治疗。所有病人均能耐受该项治疗，无严重并发症。

    【关键词】 肝肿瘤 肝动脉栓塞 32 P胶体治疗

    Clinical study on middle/advanced stage hepatic carcinoma treated with

    superselective transarterial chemoembolization of colloid 32 CrPO 4 -a Report of30cases

    Xu Xiaofeng，Ma Yubo，Wang Liangjin，et al.

    Department of Oncology，Dachang Hospital，Shanghai200436.

    【Abstract】 Objective To evaluate the efficacy of superselective transarterial chemoembolization(TACE)with colloid 32 CrPO 4 for the treatment of middle/advanced stage hepatic carcinoma.Methods Seldinger method was used for superselective TACE of proper hepatic artery.A mixed suspension of colloid 32CrPO4andchemotherapeutica-gentswasinjectedthroughthecatheter.Results TACE with colloid 32 CrPO 4 was well tolerated by the treated patients whose liver function was of Child B stagethefrequency of post-treatment hepatic insufficiency was not significantly different from that of patients treatment with routine dose of lipoidol.The colloid 32 CrPO 4 was embolized in30cases ......