【摘要】 目的 考证一日内连续多途径注射青霉素类药物导致的过敏性休克死亡。 方法 检测死者血中IgE、IL-4、组胺含量和嗜酸粒细胞数量，尸检主要靶器官病理组织学改变。 结果 检血中IgE、IL-4、组胺含量和嗜酸粒细胞数量均显著增加。死者呈窒息征象;气管喉头(会厌部)充血水肿，气管内有大量淡黄色夹有血丝的粘性液体，肺水肿，肺叶间及肺底部散在点状出血;脑膜出血和脑水肿。 结论 患者系青霉素类药物过敏性休克死亡。

    【关键词】 多途径 青霉素类药物 过敏性休克 死亡

    【Abstract】 Objective To investigate the death resulted from allergic shock by continual multi-route injected Penicillins within one day.Methods The levels of IgE，IL-4，histamine in sera and the number of acidophilic cells in blood were detected or countered，the pathohistologic alterations of the main target organs or tissues were examined.Results The levels of IgE，IL-4and histamine in sera and the number of acidophilic cells in blood were all in-creased;The asphyxiant sign ......