瑞芬太尼预防小儿丙泊酚注射痛的临床研究
瑞芬太尼,丙泊酚,疼痛,瑞芬太尼,利多卡因,小儿,1资料与方法,2结果,3讨论,4结论,参考文献
【摘要】 目的 比较小儿麻醉诱导时预先注射瑞芬太尼预防丙泊酚注射痛的效果。 方法 120例拟行静脉麻醉诱导的患儿(3~12岁),随机分为瑞芬太尼预先注射组[A组,0.5μg/(kg·min),持续60s]、利多卡因0.5mg预先注射组(B组)和混合注射组(C组),每组40例。记录丙泊酚注射痛、患儿应答、诱导后血流动力学变化、意识消失时间及该时刻丙泊酚用量、诱导期不良反应。 结果 A组注射痛发生率和严重程度显著低于B、C两组(P<0.05)。三组用药后血压均明显下降,A组心率亦下降,意识消失时间及丙泊酚用量无差异。 结论 预防小儿丙泊酚注射痛,提前60s预注0.5μg/(kg·min)的瑞芬太尼优于利多卡因0.5mg/kg预先注射或与丙泊酚混合注射。【关键词】 丙泊酚 疼痛 瑞芬太尼 利多卡因 小儿
Prevention of propofol-induced injection pain in children by remifentanil pretreatment
Wang Chen,Yuan Zhihao,Ma Weigen.
Department of Anesthesiology,Tianjin Children's Hospital,Tianjin300074.
【Abstract】 Objective To compare the efficacy of pretreatment with remifentanil on injection pain of propofol with lidocaine prior to or mixed with propofol.Methods 120patients undergoing elective intravenous anesthesia(aged3~12,ASAⅠ~Ⅱ)were randomly divided into3groups,remifentanil group(Group A,n=40),lidocaine pretreatment(Group B)or mixture(Group C)groups(n=40,respectively).Besides the vital signs(HR,MAP,SpO 2 ),the efficacy of each agent(the incidence and severity of pain on injection of propofol),ratio of answering ques-tions ......
您现在查看是摘要页,全文长 11364 字符。