摘 要： 目的 评价DiamoxSPECT脑血流(CBF)负荷显像对于老年期痴呆的诊断价值。方法 采用Diamox药物负荷^99m Tc-ECDSPECT核素显像技术对Alzheimer型痴呆(DAT)患者10例、血管性痴呆(VD)患者20例、正常对照者15例进行脑血管储备功能测定。结果 安静状态下，两痴呆组平均脑血流量均显著低于对照组(P<0.01)，不同程度VD组间脑血流无统计学意义。Diamox负荷后VD组血流增加值(△CBF)显著减少，并且各VD组间出现显著差异。而DAT组变化不明显。结论 Diamox药物负荷SPECT脑灌注显像技术是一种较为完善的脑功能检测手段，它有助于早期发现脑血管储备功能受损的代偿期患者，判断病情程度及鉴别老年期痴呆的不同类型。

    中图分类号：R742 文献标识码：A 文章编号：1003-2754(2000)04-0218-03

A study on cerebrovascular reserve capacity of patients with senile dementia

XU Jing ZHENG Li-sha ZHANG Yan-jun.

    ( Department ofNeurology,The First Affiliated Hospital of Dalian Medical College,Dalian 116011,China )

Abstract: Objective To evaluate the diagnostic valueof Diamox stress SPECT cerebral blood flow (CBF) imaging technique in senile dementia.Methods Cerebrovascularreserve capcity (CRC) in patients with senile dementia was analyzed by pre-and post-Diamoxstress SPECT using ^99m Tc-ECD. The patients were divided into two majorgroups:dementia of Alzheimer ^......