急性脑血管病与多脏器衰竭
多脏器功能衰竭|急性脑血管病,关键词：
关键词：多脏器功能衰竭；急性脑血管病
摘 要：目的 研究208例急性脑血管病并发多脏器衰竭(MOF)的死亡病例的临床特点和治疗对策。方法 208例患者按出血梗死及不同年龄、既往合并慢性疾病情况及是否存在肺部感染分成不同组并对比研究。结果 脑出血组并发MOF的严重程度重于脑梗死组(P<0.01)，年龄60～70岁组发生MOF的数量较年龄小于60岁组的明显增多(P<0.05)，同时发现既往患两种及两种以上慢性疾病的患者发生MOF的机会明显多于慢性疾患少于两种的患者(P<0.05)。合并肺部感染组发生MOF的数量、严重程度评分均明显高于非感染组(P<0.01)，存活时间明显缩短(P<0.05)。通过相关分析发现，既往所患的慢性疾病数量与MOF的数量成正相关(R=0.374，P<0.01)，且MOF的数量及评分及存活时间成负相关(R=-0.388，P<0.01;R=-0.504,P<0.01)。结论 肺部感染和既往慢性疾病是MOF发生的重要因素。
中图分类号：R743.3 文献标识码：A 文章编号：1003-2754(2000)04-0227-03
Acutecerebrovascular disease and multiple organ failure
ZHAO Xing-quan LONG Jie
( Beijing TiantanHospital 100050 China )
Abstract: Objective To study characters of 208patients with acute cerebrovascular disease that died of multiple organ failure (MOF) andprovide more useful methods to control MOF. Methods 208 cases were divided into several different groupsaccording to cerebroinfarction and cerebrohemorrhage,different ages,quantities of pastchronic diseases,with or without pulmonary infection. Compared and analyses difference andcorrelation between and within these groups. Results MOF scores of hemorrhage group were significant more thaninfarction group,(P<0.01);Organs suffere from MOF happened in age between 60-70 yearsold were more than age under 60 years old (P<0.05);quantity of organs with MOF happenedin group with two or more than two kinds(P<0.05) ； quantity of MOF and MOF scores in group with pulmonayinfection were much more than group without infection (P<0.01),and survive periods wereless than it as well (P<0.05). The study revealed that quantity of organs with MOFshowed positive correlation with sorts of chronic diseases existedprior,(R=0.374,P<0.01) ......
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