关键词:中海胃痛茶;胃溃疡;胃酸;小鼠;大鼠;豚鼠
摘要 笔者采用中海胃痛茶灌胃实验,治疗小鼠应激型胃溃疡、大鼠幽门结扎型和醋酸损伤型胃溃疡,结果表明其具有显著的抗溃疡作用。尚能明显减少小鼠扭体反应次数和对抗氯化钡所致豚鼠离体回肠收缩,降低大鼠胃液总酸度,但对胃液总量、胃蛋白酶活性、小鼠胃肠运动、出血和凝血时间的作用不明显。提示中海胃痛茶具有解痉、镇痛和抗溃疡作用。为临床应用中海胃痛茶治疗胃溃疡提供实验依据。
Anti-gastric ulceractivity of Zhonghai Weitongcha
Huang Fengjia,Nong Xingxu,Li Mao.
Guangxi Institute of Traditional Medical and Pharmaceutical Sciences(Nanning 530022)
Abstract This test is to furnish evidencefor clinical use of the Zhonghai Weitongcha.The results showed this product signficantlyprotected mice from stress ulcer,rats from gastric ulcer induced by pyloric ligation andby acetic acid.In addition,acetic acid-induced swing response in mice and BaCl2 -inducedcontraction of isolated guinea-pig ileum were antagonized.The acidity of gastric juice inrats decreased.But no influence on the volume and pepsin activity of gastricjuice,gastroenteric movement,bleeding time(BT) and coagulating time(CT) was found.It issuggested that this product has actions of anti-spasm,stopping pain and antiulcer.
Key words Zhonghai weitongcha;Gastriculcer;Acidity of gastric juice;Mice;Rat;Guinea-pig
中海胃痛茶由党参、砂仁、神曲等中药制成 ......
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