N－异丙基丙烯酰胺_聚N－异丙基丙烯酰胺

温度敏感性水凝胶的合成和性能研究

http://www.100md.com 《黑龙江医药科学》 1999年第2期

N－异丙基丙烯酰胺|聚N－异丙基丙烯酰胺|生理活性|相变温度,关键词：

     张义英秦世武张志娟姜桂英黄树华张义英秦世武：佳木斯大学医学院制药厂；张志娟姜桂英黄树华：岗市矿物局多种经营总公司医院黑龙江医药科学 1999 0 22 2

    关键词：N-异丙基丙烯酰胺；聚N-异丙基丙烯酰胺；生理活性；相变温度期刊 hljyykx 0 调查与实验研究 fur -->

提要本文采用两种不同方法合成N-异丙基丙烯酰胺(NIPA)，并以此单体与交联剂和引发剂等合成聚N-异丙基丙烯酰胺(PNIPA)。并对凝胶性质作研究，实验证明PINPA的相变温度33℃左右，能保持物质的生理活性，在生物、医学方面有极高的利用价值。

Study on the synthesis and natureof temperature sensitive water jelly

Zhang Yiying, et al

Abstract N-isopropylacrylamide (NIPA) were synthesized by two different ways. poly N-Isopropyl acrylamide(PNIPA) was synthesized with the monomer of NIPA, cross linking agent and initialor et al.We studied on the property of jelly. The results showed that the phase change temperatureof PNIPA is about 33℃ in which PINPA kept its physilogical activity. It is very valuablein the utilization in the biology and medicine.

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