龙子江 马建元 吕晓英 李守好 龙子江 李守好 安徽中医学院药理室，合肥230038；马建元 解放军第105医院，合肥230031；吕晓英 安徽中医学院第一附院，合肥230038) 中药新药与临床药理 1999 0 10 6


    关键词：爽咽茶；药理学；金黄色葡萄球菌；药物作用；肺炎球菌；药物作用；金黄色葡萄球菌；微生物学；肺炎球菌；微生物学 期刊 zyxyylcyl 0 药效与毒理学研究 fur -->


    

摘要：采取试管法进行体外抗菌试验，证明爽咽茶对金黄色葡萄球菌、肺炎球菌、甲链、乙链大肠肝菌及肺炎克雷伯菌等有明显的抑制作用；对金黄色葡萄球菌的作用最强，MIC₅₀ 为3.03125g/ml；对大肠肝菌作用最差，MIC₅₀ 为1g/ml。体内抗菌试验测得爽咽茶对金黄色葡萄球菌和肺炎克雷伯菌感染小鼠有明显的保护作用，其ED₅₀ 分别为3.365g/kg和4.189g/kg。

    中图分类号：R285.5；R378.1 文献标识码：A 文章编号：1003-9783(1999)06-0360-02

A Study on Antimicrobial Effect of Shuangyan Tea

LONG Zi-jiang, MA Jian-yuan, LU Xiao-ying, et al

    (Department of Pharmacology Anhui Collage of TCM,Hefei 230038)

Abstract :Antimicrobial test in vitro showed that Shuangyan Tea can considerably inhibit the growth of staphylococcus aureus, Diplococcus pneumoniae, α-Streptococcus, β-Strep, Escherichia coli, Klebsiella pneumoniae. The bocteriostatis effect an Staphylococcus aureus is most potent and MIC₅₀ is 0.0325 g/ml,while that on Escherichia coli is lowest and MIC₅₀ is 1 g/ml.Antinricrolial test in vivo showed that the tea can evidently protect the mice infected by aureus and klebsiella pneumoniae,ED₅₀ being 3.002 g/kg and 4.189 g/kg respectively.

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