学习_记忆_发育_大鼠不同类型学习记忆的发育变化研究

大鼠不同类型学习记忆的发育变化研究

http://www.100md.com 《中国行为医学科学》 1998年第4期

学习|记忆|发育,关键词：,【摘要】目的,方法,结果,结论,Developmentalchangesoflearningandmemoryinrats,【Abstract】Objective,Methods,Results,Conclusions,【Keywords】,材料与方法,结果,表1发育早期和成年大鼠AAR习得的比较(±s),表2发育

     熊鹰蔡文琴李希成隋建峰熊鹰，李希成，隋建峰，第三军医大学生理教研室，重庆，400038；蔡文琴，第三军医大学组胚教研室，重庆，400038 中国行为医学科学 1998 0 7 4

    关键词：学习；记忆；发育期刊 zgxwyxkx 0 论著 fur -->

【摘要】目的 研究发育过程中不同类型学习记忆的变化特点.方法采用主动回避反应(AAR)、被动回避反应(PAR)、空间分辨记忆(SDM)和味觉厌恶条件反射(CTA)四种模式对学习和记忆过程进行系统研究。结果 2月龄(2m)大鼠在AAR、PAR两种模式中，学习和记忆成绩最好，1m大鼠成绩最差；在SDM测试中，2m、6m大鼠的训练和测试成绩都强于1m大鼠；以足电震为非条件刺激的CTA模式中，年龄越小建立越快。结论大鼠发育过程中，不同类型的学习记忆有独特的时间出现过程.

Developmental changes of learning and memory in rats Xiong Ying,Cai Wenqin,LiXicheng,et al. Department of Physiology,Histology and Embriology, Third Military MedicalUniversity,Chongqing 400038

【Abstract】 Objective To observe the developmental changes of learningand memory in different models in rats. Methods Several behaviour models such asactive avoidance reaction(AAR), passive avoidance reaction(PAR), spatial discrimination memory(SDM) ,conditioned taste aversion(CTA) were used to research the ontogeny oflearning and memory .Results 2-month-old rats show the best ability in theacquisition and retention of AAR and PAR,1-month-old rats learn more slowly than that of2-month and 6-month-old rats;Both of 2-month and 6-month- old rats are more efficient inacquisition of SDM in 8-arm radial maze than that of 1-month-old rats;10-day-old ratslearn more rapidly than 21-day and 2-month-old rats in CTA which saccharin is paired withfootshock.Conclusions Different types of learning and memory emerged according todifferent developmental timetables.

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