Comparison of triple therapy with lansoprazole or famotidine for Helicobacter pylori-associated duodenal ulcer
Subjectheadings Helicobacterpylori|helicobacterinfections,drugtherapy|pepticulcer,drugtherapy|famotidine,therapeuticuse|amoxicillin,therapeuticuse|omeprazole,analogsandderivatives,ComparisonoftripletherapywithlansoprazoleorfamotidineforHelicobacterpylori-asso
关键词：Subject headings Helicobacter pylori; helicobacter infections/drug therapy; peptic ulcer/drug therapy; famotidine/therapeutic use; amoxicillin/therapeutic use; omeprazole/analogs and derivatives
Abstract
AIM Tomake a comparative study of a triple therapy with lansoprazole or famotidine for H.pylori-associated duodenal ulcer.
METHODS Sixty patients with activeDU were randomly allocated to two groups: the first group received lansoprazole (30mg, qd)for 4 weeks plus amoxycillin (500mg, qid) and gentamycine (40mg, tid) for 2 weeks; thesecond group received famotidine (20mg, bid) for 4 weeks, plus amoxycillin (500mg, qid)and gentamycine (40mg, tid) for 2 weeks. Clinical, endoscopic and bacteriologicalevaluations were made 1 month after the treatment.
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