骨髓基质细胞修复关节软骨缺损的实验研究
骨髓基质细胞|软骨|修复,关键词:
关键词:骨髓基质细胞;软骨;修复
摘要:目的 研究骨髓基质细胞对关节软骨缺损的修复效果。方法 抽取兔骨髓基质细胞在体外扩增,将其混合于Ⅱ型胶原凝胶内,再植入体内,观察其对兔膝关节软骨缺损的修复效果。结果 软骨缺损由类似于透明软骨的组织修复,3个月后未见软骨退变。结论 骨髓基质细胞对关节软骨具有修复能力,可望成为临床上修复关节软骨的新方法。
中图分类号:R681.5+2 文献标识码:A
文章编号 :1007-5496(2000)10-1508-02
Experimental Study ofrepairing the defects of articalar cartilage with
DAI LIan sheng DONG Qi rong ZHENGZu gen
(Orthopaedic Department,Wuxi No.3 Hospital Wuxi 214041,China)
Abstract:Objective To investigate the value of bonemarrow stromal cells(BMSCs)on the repair of articular cartilage defect.Method CulturedBMSCs were embedded in collagen Ⅱ gel were placed in the artificial articular cartilagedefects of
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