张祥宏 卜玉华 王俊灵 严霞 米建民 赵文元 张振国 杨永滨 三角顺一 青木一雄 张祥宏(河北医科大学病理研究室 石家庄市 050017)；卜玉华(河北省赞皇县医院)；王俊灵(河北医科大学病理研究室 石家庄市 050017)；严霞(河北医科大学病理研究室 石家庄市 050017)；米建民(河北省赞皇县医院)；赵文元(河北医科大学病理研究室 石家庄市 050017) 中国肿瘤临床 2000 0 27 7


    关键词：胃蛋白酶原；检测；胃癌；随访；胃粘膜；癌前病变 期刊 zgzllc 0 论著 fur -->


    

摘要 目的：探讨临床T_1～2 N₀ M₀ 乳腺癌患者腋窝淋巴结转移(ALNM)的高危因素。方法：采用回顾性病例对照研究，对256例乳腺癌患者进行单因素及多因素Logistic回归分析。结果：多因素分析显示微淋巴管浸润、肿瘤大小、肿瘤部位、癌周浸润、间质浸润等5个指标进入Logistic回归方程，P值分别为0、0.005 6、0.023 9、0.022 5和0.030 1。结论：微淋巴管浸润、肿瘤大小、肿瘤部位、癌周浸润、间质浸润等为临床T_1～2 N₀ M₀ 乳腺癌患者ALNM的高危因素；了解高危因素，有助于临床准确判断ALNM情况。

Study on the Risk Factors of Axillary Lymph Node Metastases in Patients with T_1-2 N₀ M₀ Breast Cancer

Xie Derong,Yao Herui,Chen Daijia,et al.

    (Department of Oncology,Sun Yatsen Memorial Hospital,Sun Yatsen University of Medical Sciences,Guanzhou)

Abstract Objective：To investigate the risk factors of axillary lymph node metastases (ALNM) in patients with T_1～2 N₀ M₀ breast cancer.Methods：256 cases of T_1～2 N₀ M₀ breast cancer were studied using retrospective analysis,control study,single and multi-factors logistic regression analysis.Results：Multi-factors logistic regression analysis showed that 5 factors including microlymphatic invasion,diameter of primary tumor,location of tumor,circumferential and stromal invasion entered the logistic equation,the p values were 0,0.0056, 0.0239, 0.0225, 0.0301 respectively.

    Conclusions：Microlymphatic invasion,diameter of primary tumor,location of tumor,

    circumferential and stromal invasion were the risk factors of ALNM.Learning the risk factors might be good for clinician to predicate the status of ALNM more exactly.

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