关键词:药物疗法/化学诱导;口腔肿瘤;组织学
摘要 用氨甲喋呤、5-氟脲嘧啶、顺铂等联合化疗23例口腔鳞癌患者,近期疗效中:CR34.78%,PR47.83%,NR17.39%,同时分析了术后原发灶、区域淋巴结的组织学改变。结果显示:无论临床反应如何,组织学上均有不同程度的退行性变。指出癌瘤原发灶及转移灶临床消失者部分组织学检查仍可查出阳性(50%),为该病的临床治疗提供了有力的依据。
Relationship between the curativeeffect by induced chemotherapy and the histology modification in mouth squamous carcinoma
Yao Jinguang
Department of stomatology, Youjiang Medical College for National Minorities, Baise,Guangxi, 533000
23 patients with mouth squamouscarcinoma were combinedly treated with MTX, 5-FU, DDP. The curative effect of near stagewas: CR34.78%, PR47.83%, NR17.39%, and the post-operational primary focus, histologymodification of the regional lymph node were also analysed. Results showed that clinicreaction will result in variaty retrograde affection of histology. It indicated that theirhistology tests turned out to be positive in patients (50%) with clinic disappearance ofprimary and metastatic focus. This can be the basis for clinical treatment.
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