阿莫西林_稳定性_最稳定(pH)m

pH及不同缓冲盐对阿莫西林化学稳定性的影响

http://www.100md.com 《沈阳药科大学学报》 1999年第3期

阿莫西林|稳定性|最稳定(pH)m|缓冲盐,关键词：,.

     王齐放李三鸣赵吉吉朱瑛沈阳药科大学基础部，沈阳 110015 沈阳药科大学学报 1999 0 16 3

    关键词：阿莫西林；稳定性；最稳定(pH)m；缓冲盐期刊 syykdxxb 0 研究论文 fur -->

摘要 根据化学动力学的原理，采用经典法及单测点法,考察了pH对阿莫西林化学稳定性的影响，同时，对不同种类的缓冲盐对其降解作用也进行了考察.结果表明阿莫西林的最稳定(pH)_m为6.2～7.2，在醋酸盐及磷酸盐缓冲液中较稳定.

分类号 R913

Effects of pH and Different Buffer Salts on Amocillin's Chemical Stability

Wang Qifang,Li Sanming,Zhao Zhe,Zhu Ying

Department of Basic Coureses,Shenyang Pharmaceutical University,Shenyang 110015

Abstract According to the chemical kinetics principle,twomethods-the classical method and the single point method were used in this paper to studyhow the pH affected amocillin′s chemical stability and how amocillin degradated indifferent buffer salts. The results showed that amocillin′s pH of maximum stability was6.2～7.2 ......

百拇医药网 http://www.100md.com/html/DirDu/2005/07/04/66/57/31.htm

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