关键词:开心胶囊;急性毒理实验;慢性毒理实验;大鼠;小鼠
摘要 开心胶囊Ⅱ号是治疗无症状心肌缺血的验方。按最大灌胃量及最高浓度,进行了NIH小鼠的急性毒理实验;并设10g/kg、6g/kg、0.1g/kg、对照组观察了清洁级SD大鼠为期半年的慢性毒理实验。结果显示,急、慢性毒理实验均未见到开心胶囊Ⅱ号有明显毒理反应。
中图法分类号 R965.3
STUDY ON THE LONG-TERM AND SHORT-TERM TOXICITY OF HAPPY CAPS-Ⅱ
Wang Xiao,Mai Xihuan,Chen Jinghe
(The first affiliated hospital of Guangzhou university of TCM,Guangzhou,510407)
ABSTRACT Happy Caps-Ⅱis one of the experimental recipes for treating silent myocardial ischemia(SMI).Theshort-term toxicities are studied to NIH rats by the biggest oral administration and thehighest density.The long-term toxicities are studied to clean-degree SD rats in 24 weekswith dividing into four groups (10g/kg,6g/kg,0.1g/kg and control).The results indicatethat Happy Caps-Ⅱ have no apparent toxic reaction.
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