关键词:电阻抗法;红细胞流变特性;方法评价
本文在FRICKE悬浮液电导理论基础上,利用北医设计研制的红细胞流变特性测定仪(电阻抗法)测量红细胞的松弛过程。通过大量的实验证明,该仪器所测值确实能够反映出红细胞的流变特性,其稳定性和重复性也较好。变异系数均小于5%,并且与激光法测量值有较好的相关性。该测量方法虽受红细胞压积和悬浮介质电导率的影响和限制,但只要在仪器测量范围内,严格控制压积的一致性,其测量的重复性和准确性是可以保证的。
分类号: R318.01; R331.141
MEASUREMENT OF RBCRHEOLOGICAL BEHAVIOURS
WITH IMPEDANCE METHOD
Yang Yueping, Ma Weiyuan, Sun Dagong, et al
(Department of Medical Physics,Beijing Medical University)
ABSTRACT On the basis of Frich-Velick'stheory on conductivity of red blood cell (RBC) suspension, we studied the relaxationprocess of RBC with an erythrocyte rheometer (impedance method) developed by BeijingMedical University. It was shown from the results that this kind of method can reallyreflect the rheological properties of RBC with good stability and reproducibility. Thecoefficient of variation CV was lower than 5%, and comparing with that of ektacytometry,we found that there was a good correlation between the measuring results of the twomethods.
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