许树旭 王文信 方树青 许树旭 王文信 方树青(中国人民解放军第266医院 承德 067000) 解放军药学学报 1999 0 15 4


    关键词：普罗布考；非诺贝特；藻酸双脂钠片 期刊 jfjyxxb 0 论著 fur -->


    

摘 要 目的： 观察比较新药普罗布考片与其它两种降血脂药的降脂作用。方法： 197例高脂血症患者随机分组，分别口服藻酸双酯钠片(100mg，tid)、非诺贝特片(100mg.tid)和普罗布考片(250mg.bid)。于第4周、第8周抽空腹血测定血脂值。结果： 服药8周后，普罗布考组降血清总胆固醇(TC)总有效率84.4%；藻酸双酯钠组和非诺贝特组分别为75.5%和75.9%。服普罗布考期间，仅发现少而轻的不良反应。结论： 普罗布考片为安全显效的降血脂药。

    中图分类号 R966

COMPARISON OF EFFECTS ON PROBUCOL AND THE TWO OTHER LIPIDEMIA-LOWERING DRUGS

Xu Shuxu,Wang Wenxin,Fang Shuqing

    (The 266th Hospital of PLA,Chengde 067000)

Abstract AIM To compare the effects of Probucol with polysaccharide sodium(p.s.s) and fenofibrate.METHODSThe blood lipid was derermined in 197 patients with hyperlipidemia treated with probucol,p.s.s and fenofibrate after 4 and 8 weeks respectively.RESULTS The total effectve rate of probucol was 84.4%,while the effective rate of two other agent was 75.5 and 75.9% respectively.CONCLUSION Probucol tablets are safe and effective in lowering bloodlipid.

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