关键词:冠状动脉疾病;脂蛋白类;甘油三酯
摘 要:目的 探讨甘油三酯/高密度脂蛋白胆固醇(TG/HDL-C)比值对冠心病(CHD)的诊断价值。方法 分析173例选择性冠状动脉造影(冠脉造影)确诊的CHD患者(CHD组)及118例冠脉造影阴性者(对照组)的TG/HDL-C比值水平与CHD之间的关系。结果 CHD组患者的TG/HDL-C比值水平及异常率均明显高于对照组(2.02±1.19vs 1.40±0.97,P<0.01,28.9%比11.8%,P<0.01)。经多元逐步回归分析显示:与TG、HDL-C相比,该比值与CHD之间显示了更有意义的回归关系(β值0.25,P值=0.0001,复相关系数为0.45)。结论 TG/HDL-C比值对于CHD诊断是一有临床使用价值的指标。
Thepredictive value of TG/HDL-C ratio for coronary heart risk
ZHANG Ming HUO Haiyang LI Zhanquan, et al.
( Liaoning ProvincialHospital, Shenyang 110015, China )
Abstract : Objective To study the significance ofserum triglycerin/high density lipoprotein-cholesterol (TG/HDL-C) ratio in predictingcoronary heart disease(CHD) risk. Methods TG/HDL-C ratios were analysed in 291 cases underwentcoronary angiogaphy (CHD was present in 173 patients and absent in 118 as normal controlgroup). Results TG/HDL-C ratio and abnormal rate of the ratio weresignificantly higher in patients with CHD than those of the normal control group(P<0.01). Multivariate regression analysis revealed that the ratio was a significantvariable associated with CHD compared with either TG or HDL-C. Conclusion High TG and low HDL-Cconcentrations are much more dangerous factor in developing CHD than single blood lipidabnormality and thus TG/HDL-C ratio is a better predicting index for CHD risk.
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