关键词：帕金森病；微电极记录；定向；手术
摘要 目的：介绍微电极记录技术在治疗帕金森病中的作用。方法：采用微电极细胞电生理记录技术进行术中靶点监测，对100例帕金森病患者行苍白球腹后部(96例)和丘脑腹外侧核(4例)毁损术，患者术前及术后评估采用UPDRS积分，术中靶点更换率为87%。结果：手术效果优良，有效率100%，原有症状术后显著改善率平均达89.4%，无永久并发症。结论：微电极的应用能显著减少手术并发症的发生，提高手术效果。
The role of microelectrode recordingin operation for Parkinson's disease Gao Guodong, Zhang Hua, Zhang Baoguo, et al. Department ofNeurosurgery Tandu Hospital of the Fourth Military Medical University. Xi'an 710038
Abstract Objective: To introduce the roleof microelectrode recording in operation for Parkinson's disease. Methods:One hundredpatients underwent pallidotomy and thalamotomy for Parkinson's disease by means ofmicroelectrode recording used as intraoperative target localization between Oct. 1997 andApr. 1998. The patients were assessed by means of UPDRS. Results: The change rate oftargets is 87% and the outcome is excellent, every patient shows improvement and obviousrelief of symptoms is about 87.4%. No patient shows permanent complication. Conclusion:The author regards microelectrode recording can decrease the rate of complication and givea better outcome.
Key words Parkinson's disease Microelectrode recording Stereotaxy Operation
帕金森病的定向外科手术治疗的效果与术中毁损靶点的精确定位有重要的直接关系 ......
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