关键词:系统性红斑狼疮;消化系统;结核
【摘要】 目的 探讨系统性红斑狼疮(SLE)消化系统累及的发生率及临床表现。方法 对1990年1月~1997年7月北京协和医院诊断明确资料完整的277例SLE住院病例进行分析。结果 其中有消化系统症状体征或实验室异常者多达157例,占56.7%。98例(35.4%)无明确酒精、药物、感染病因,且与SLE活动性有关(P<0.01)。值得注意的是:44例以胃肠病变为首发或主要表现的SLE病例中,误诊39例(88.6%),最易误诊为感染性疾病,尤其是结核,其次为其它自身免疫性疾病及肿瘤。结论 SLE消化系统表现的发生率高,容易误诊,临床应引起重视。
D igestive system involvement in systemic lupus erythematosus
ZHANG Xuan, ZENG Xuejun, DONG Yi, et al.
Pecking Union Medical College Hospital, Beijing, 100730
【 Abstract 】 Objectives To investigate the clinical manifestations of digestive system involvement in systemic lupus erythematosus (SLE). Methods Two hundred and seventy-seven inpatients concordant with the diagnostic criteria of SLE in this hospital since 1990 were analyzed retrospectively. Results Among these, 157(56.7%) had symptoms, signs and laboratory abnormalities of digestive system. involvement. 98(35.4%) could only be ascribed to SLE istelf, and were concordant with lupus activity(P < 0.01). It was noteworthy that in 44 cases gastrointestinal involvements were the presenting manifestations of SLE, of which 39 were misdiagnosed(88.6%) as infectious disease, in particular, tuberculosis, other autoimmune disease or tumor. Conclusions Digestive system involvements occur with high frequency in SLE and are easily misdiagnosed which should not be overlooked.
【 Key words 】 Systemic lupus erythematosus Digestive system Tuberculosis
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