邓志华 蔡洪培 李石 沈健伟 200003 上海，第二军医大学长征医院 中华消化杂志 1999 0 19 5


    关键词：端粒酶；腹水；鉴别诊断 期刊 zhxhzz 0 论著 fur -->


    

【摘要】 目的 检测腹水脱落细胞端粒酶活性，为临床鉴别诊断提供依据。方法 收集各种类型腹水脱落细胞，用TRAP-PCR-ELISA银染法检测腹水脱落细胞端粒酶活性。结果 肝硬化、结核性腹膜炎腹水脱落细胞不能检出端粒酶活性，而癌性腹水85.29%端粒酶阳性。结论 癌性腹水端粒酶阳性。端粒酶活性检测可作为临床良恶性腹水鉴别诊断依据之一。

The differential diagnostic value of telomerase activity in benign and malignant ascites

DENG Zhihua ， CAI Hongpei, LI Shi, et al.

    Department of Gastroenterology Changzheng Hospital, Second Millitary Medical University, Shanghai 200003

【 Abstract 】 Objective To detect the telomerase activity in ascitic exfoliative cells so as to provide scientific basis for differential diagnosis. Methods To harvest the cells in various kinds of ascitic fluid and detect the telomerase activity by TRAP-ELISA. Results Telomerase activity could not be detected in ascites of hepatic cirrhosis and tuberculous peritonitis but could be detected in 29 out of 34 cancerous ascites.Conclusions Telomesase activity is positive in cancerous ascites and is usefiul in differential diagnosis of benign and malignant ascites.

     【 Key words 】 Telomerase Ascites Differential diagnosis

腹水是临床常见症状之一 ......

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