关键词：多原发性癌；内镜检查
【摘要】目的探讨本地区上消化道多原发性癌的某些临床特点。方法回顾性分析我院24年内119例上消化道多原发性癌的临床资料。结果发病高峰年龄为51～70岁，男性多于女性，体力劳动者较脑力劳动者高。同时性和异时性上消化道多原发性癌两癌灶发生的平均间隔时间分别为0.12个月和4.7年；同时性和异时性食管多原发性癌、胃多原发性癌和食管、胃多原发性癌的好发部位分别为食管中段-下段、胃窦-贲门和食管中段-胃体；癌灶手术后病理检查以食管鳞状细胞癌和胃粘液腺癌多见。结论内镜检查时仔细观察上消化道全程，结合每处癌灶及癌灶间粘膜活检有助于提高上消化道多原发性癌的诊断水平。
Multiple primary cancers of upper gastrointestinal tract
XIA Jinrong, MIAO Cailiang.
( Affiliated Hospital of Zhenjiang Medical College, Zhenjiang 212001, China )
【 Abstract 】 Objective The clinical features of multiple primary cancers in upper gastrointestinal (UGI) tract were studied. Methods 119 cases with such cancers were encountered in our hospital through past 24 years ; the documents collected and reviewed. Results Regarding incidence, 51 - 70 years of age appeared to be the peak ; males > females; physical laborers > sedentary workers . The average interval when multiple cancers were discovered “ synchronously ” or “ metachronously ” varied from 0.12 month to 4.7 years respectively ,the most frequent sites involved were mid - lower esophagus, cardia ,and antrum of stomach . Pathology of resected specimens often showed malignant squamous cells (esophagus) and mucoid adenocarcinomas (stomach). Conclusion During gastroscopy meticulous observation throughout the UGI tract and taking biopsies from sites between suspected lesions are mandatory to reveal multiple primary cancers.
【 Key word 】 Multiple primary cancers; Endoscopy
上消化道多原发性癌(以下简称上消化道多发癌)临床上较为少见 ......
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