胃增生性息肉_癌变_异型增生_胃增生性息肉癌变

胃增生性息肉癌变

http://www.100md.com 《中华消化内镜杂志》 1999年第3期

胃增生性息肉|癌变|异型增生,关键词：,Malignanttransformationofgastrichyperplasticpolyp

     聂玉强李瑜元杜洪陈金培吴惠生聂玉强、李瑜元、吴惠生广州市第一人民医院消化科510180；杜洪、陈金培病理科中华消化内镜杂志 1999 0 16 3

    关键词：胃增生性息肉；癌变；异型增生期刊 zhxhnjzz 0 论著 fur -->

【摘要】目的 探讨胃增生性息肉(GHP)的癌变及其机制。方法回顾性研究144例GHP和23例胃腺瘤(AD)的临床和病理特点。结果 GHP中，57.6%，分布在胃窦，61.1%无蒂，平均直径(10.5±9.7)mm,合并异型增生15例(10.4%)，合并肠化生25例(17.4%)，癌变3例，癌变率2.1%，直径分别为12、25和23mm。AD中，69.6%分布在胃窦，有蒂占60.9%，平均直径(13.7±6.9)mm，6例(26.1%)合并肠化生，2例癌变，癌变率8.7%，直径是25和30mm。癌变者均为高分化腺癌。结论 GHP的癌变率低，但的确存在癌变，癌变与GHP合并异型增生及肠化生有关。

Malignant transformation ofgastric hyperplastic polyp

NIE Yuqiang,LI Yuyuan,DU Hong,et al.

Department of Gastroenterology and Pathology,First Municipal People's Hospital ofGuangzhou,Guangzhou 510180

【Abstract】 Objective Thecharacteristics of malignant transformation from gastric hypreplastic polys(GHP) werestudeid.Methods A number of 144 GHPs and 23 adenomas(ADs) was reviewedwith special reference to intestinal metaplasia,dysplasia and malignant transformation.Results Abouthalf of GHPs located at gastric antrum,sessile in shape,sized 10.5±9.7mm in diameter inaverage,being associated with dysplasia in 15(10.4%) and intestinal metaplasia in25(17.4%).Focal malignancy was detected in 3 GHPs with a size as large as 12,23 and 25mmin diameter.About 60～70% of ADs looked pedunculated,sited at antrum,sized 13.7mm indiameter.Only 6 ADs (26.1%) had intestinal metaplasia.Well differentiated adenocarcinomawas found in 2 ADs(8.7%) with a huge size of 25～30mm in diameter. Conclusion Malignanttransformation from GHP was incidental,if any ,being closely related with intestinalmetaplasia and dysplasia.

......

百拇医药网 http://www.100md.com/html/DirDu/2005/07/06/64/76/90.htm

您现在查看是摘要页，全文长 12183 字符。