关键词:前列腺肿瘤;癌;基因
【摘要】 目的 探讨上皮细胞粘附因子E-cadherin在前列腺癌组织中的表达及其与前列腺癌预后的关系。 方法 采用免疫组织化学染色法检测42例前列腺癌标本E-cadherin的表达。 结果 40.5%表达阳性,42.8%表达不同程度下降,16.7%表达阴性。肿瘤恶性程度越高,其表达异常所占比率越高。确诊时即已发现肿瘤转移和随访中相继出现转移的患者E-cadherin表达下降比率均高于全组,分别为83.3%和77.7%。 结论 E-cadherin在前列腺癌组织中表达异常的比率随着肿瘤分级的升高而增加,E-cadherin的表达状况对前列腺癌的预后有一定参考价值。
The investigation of E-cadherin expression and its prognosis significance in prostate cancer
MAO Quanzong, XU Fengji
Department of Urology, Peking Union Medical College Hospital, Bejing 100730
【 Abstract】 Objective To understand theexpression of E-cadherin and its correlation to the grade and prognosis of prostatecancer. Methods E-cadherin expression of42 prostate cancer samples were studied with immunohistochemical staining. Results 40.5% specimens werepositive ......
您现在查看是摘要页,全文长 10331 字符。