章振保 张时纯 齐范 黎明 纪印周 515031 广东省汕头大学医学院第二附属医院泌尿外科(章振保、纪印周、黎明)；湖南医科大学附属湘雅医院泌尿外科(张时纯、齐范) 中华泌尿外科杂志 1999 0 20 7


    关键词：前列腺增生症；尿道梗阻 期刊 zhmnwkzz 0 论著 fur -->


    

【摘要】 目的 探讨前列腺增生症(BPH)致膀胱流出道梗阻(BOO)，及其相关问题。 方法 采用排尿期尿道测压(MUPP)检测43例BPH患者，以压力下降梯度(MUPPG)计算梗阻程度，同时行膀胱等容收缩试验测最大逼尿肌等容收缩压(Piso)；进行国际前列腺症状评分(IPSS)，经腹壁B超测前列腺体积(V)。 结果 43例BPH中38例存在BOO(88%)，梗阻位于膀胱颈部28例(77%)；MUPPG与IPSS、V、Piso呈正相关。 结论 MUPP能检测并计算BOO程度；BOO是BPH的病理基础，临床症状、逼尿肌代偿与其相关。

Clinical significance of micturitional urethral pressure profilometry in benign prostatic hyperplasia

ZHANG Zhenbao^* ,ZHANG Shichun,QI Fan,et al.

    Department of Urology,the Secend Affiliated Hospital,Medical College of Shantou University,Shantou 515031

【Abstract】 Objective To increase the understanding of clinical manifestations of benign prostatic hyperplasia (BPH). Methods 43 inpatiants with BPH were studied.Symptoms were assessed with international prostatic symptom score (IPSS).Prostate volume (V) was estimated by transabdominal ultrasonography.The maximum isometric contraction pressure (Piso) was meassured by the continuous occlusion test,and bladder outlet obstruction (BOO) was meassured by micturitional urethral pressure profilometry (MUPP).The severity of the obstruction was determined by the magnitude of the micturitional urethral pressure profile gradiend (MUPPG). Results 38 out of 43 cases suffered from BOO (88%).There were 28 cases with obstruction near bladder neck (77%).There was significant correlation between MUPPG and IPSS(r=0.5083,,P=0.003);between MUPPG and V(r=0.4472,,P=0.018);between IPSS and V(r=0.3651,,P=0.022);between MUPPG and Piso (r=0.8869,P=0.0001). Conclusions These results suggested somewhat intimate relationships among severity of BOO,prostate volume and symptoms.The increase in detrusor contractility with increasing outlet obstruction suggested a compensatory response to obstruction.

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