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尸体肾移植术后HCMV病的防治
http://www.100md.com 《中华泌尿外科杂志》 1999年第8期
肾|移植|巨细胞病毒,关键词:
     郑克立 吴培根 朱兰英 洪良庆 刘东 王长希 510080 广州,中山医科大学附属第一医院泌尿外科(郑克立、洪良庆、刘东、王长希),肾内科(吴培根、朱兰英) 中华泌尿外科杂志 1999 0 20 8


    关键词:肾;移植;巨细胞病毒 期刊 zhmnwkzz 0 论 著 fur -->


    

【摘要】 目的 探讨尸体肾移植术后人巨细胞病毒(HCMV)病的防治。 方法 应用HCMV-Ag试验诊断HCMV感染,对1150例尸体肾移植进行回顾性分析。 结果 治疗组:1989年9月~1997年4月共1050例, HCMV病45例,治愈30例,死亡15例;预防组:1997年5月~1998年5月共100例,活动性HCMV感染42例,由于进行了预防性治疗,无1例HCMV病发生和因HCMV感染而死亡。 结论 HCMV-Ag试验可以早期诊断活动性HCMV感染,指导HCMV病的有效治疗;对活动性HCMV感染积极进行预防性治疗,能显著减少HCMV病的发生。

Prophylaxis of HCMV disease forpatients undenwent cadaveric renal transplantation ZHENG Keli,WU Peigen,ZHULanying,et al.The First Affiliated Hospital, Sun Yatsen University of MedicalSciences,Guangzhou 510080

    【Abstract】 Objective To study the efficacy of prophylactictherapy of HCMV disease for patients underwent cadaveric renal transplantation. Methods HCMVinfection has been detected by means of antigenemia test in 1 150 patients underwentcadaveric renal transplantation and prophylactic management has bee instituted in 42patients before renal transplantation. Results From Sep.1989 toApr.1997,HCMV disease was detected after renal transplantation in 45 patients out of 1050. 30 have been cured of the disease while mortslity occurred in 15 in spite oftreatment.From May 1997 to May 1998,active HCMV infection was detected before renaltransplantation in 42 out of 100 and appropriate treatment was instituted beforetransplantation as a prophylactic measure.No HCMV disease occurred after the renaltransplantation and there has been no mortatlity because of HCMV disease. Conclusions Detectionand treatment of HCMV infection before renal transplantation is very beneficial to thepatients and is highly recommended.

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