关键词：前列腺肿瘤；癌；前列腺特异性膜抗原
【摘要】 目的 探讨血清PSA浓度变化与前列腺癌及其骨转移的相关性。 方法 对93例直肠指诊异常及血清PSA>4ng/ml的患者，行直肠B超引导下前列腺穿刺活检；用99mTc-MDP行全身骨扫描判断有无骨转移。 结果 93例中前列腺活检阳性者60例(64.5%)，其中26例骨扫描阳性；随血清PSA浓度升高，前列腺阳性活检率及其远处骨转移阳性率升高(P<0.01)。结论 血清PSA升高与前列腺癌及其骨转移的发生率呈正相关。
SerumPSA level and prostatic nodule on palpation in the detection of prostatic cancer
ZHONG Chenyang,WANGJianye,DENG Shumin,et al.
(De partment of Urology,the Beijing Hospital,Beijing100730,China)
【Abstract】 Objective To evaluate the serum prostate-s pecific antigen level in thedetection of prostate cancer and skeletal metastasi s. Methods Transrectalultrasound-guided needle biopsy of prostate was carried out for 93 subjects with anelevated serum PSA(>4.0ng/ml )and abnormal findings on rectal palpation.Whole body bonescintigraphy was unde rtaken for the detection of skeletal metastasis. Results 60(64.5%) ofthe 93 were diagnosed as prostatic cancer on biopsy of which 26 h ave had positive bonescan findings. Conclusions Prostat e cancer and bony metastasis were more likely when serumPSA has been elevated.
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