【摘要】 目的 探讨庚型肝炎病毒(HGV)在肝细胞癌(HCC)组织中存在状态。方法 采用抗HGV NS5单克隆抗体，以免疫组织化学法检测53例HCC患者石蜡包埋的肝癌组织。结果 HCC组织中检出HG抗原(HGAg)20例(37.7%)，在非乙非丙、乙型及丙型肝炎病毒组中，分别检出HGAg2例(25%)、16例(39%)和2例。结论 HCC患者中HGV感染较常见；HGV感染似乎不是HCC发生的高危因素。

A study of HGV infection in liver tissue of hepatocellular carcinoma LIAO Huiyu, LANG Zhenwei, ZHU Renping, et al. Youan Hospital, Beijing 100054

     【Abstract】 Objective To investigate the prevalence of hepatitis G virus (HGV) in hepatocellular carcinoma (HCC). Methods HGV NS₅ antigen was detected in paraffin-embedded HCC tissues from 53 autopsy patients by using immunohistochemical method with antiHGV NS5 monoclonal antibody.Results Among the 53 subsjects, 20(37.7%) had been detected of HGV antigen(HGAg) in HCC tissues. When serological markers were used, the HGAg detection rate was 2/8(25%) in non-B and non-C, 16/41(39%) in HBV and 2/2 in HCV infection groups, respectively. Conclusion The infection of HGV is often seen in patients with HCC. HGV infection does not appear to account for an important independent risk factor for development of HCC.

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