章渭方 陈君柱 朱建华 张芙荣 310003 杭州，浙江医科大学附属第一医院 中华内科杂志 1999 0 38 5


    关键词：X综合征；高胰岛素血症；胰岛素抵抗 期刊 zhnkzz 0 论 著 fur -->


    

【摘要】 目的 探讨X综合征患者是否存在胰岛素抵抗现象。方法 观察11例X综合征患者(X综合征组)和10例正常人(对照组)糖耐量试验时空腹和服糖后 30、 60、 120和 180分钟时血糖、血胰岛素水平和胰岛素敏感性指数的变化。结果 X综合征组和对照组空腹血糖，服糖后120及180分钟时的血糖无变化(P>0.05)；服糖后30、60分钟时的血糖X综合征组较对照组高(P<0.05);X综合征组空腹胰岛素水平和胰岛素敏感性指数比正常对照组高(P<0.05)；服糖后血胰岛素水平及胰岛素敏感性指数，X综合征组较对照组明显增高(P<0.01)。 结论 X综合征患者存在有高胰岛素血症和胰岛素抵抗。

Cardiac Syndrome X and InsulinResistance ZHANG Weifang, CHEN Junzhu, ZHU Jianhua, et al. Department of Cardiology, The First Hospital, Zhejiang Medical University,Hangzhou 310003

    【Abstract】 Objective To determine whether there is insulinresistance in patients with syndrome X. Methods By using oral glucosetolerance test (OGTT), plasma glucose and insulin levels, and insulin sensitivity index (ISI) were measured in 11 patients with syndrome X and in 10 sex and age matched normalsubjects as controls. Results The syndrome X group had a higher fasting insulin leveland ISI than the control group (P<0.05). After oral glucose, plasma insulin level andISI in patients with syndrome X were significantly higher than the control group(P<0.01). Conclusion In patients with syndrome X there arehyperinsulinemia and insulin resistance.

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