关键词:肿瘤转移;骨;外科手术;预后
【摘要】目的 报道手术治疗骨转移癌的临床经验。方法 1988年2月~1997年3月共手术治疗骨转移癌89例。其中男58例,女31例。年龄10~74岁,其中41~70岁72例,占80.9%。其最好发部位分别是脊柱23例,股骨22例和骨盆13例,而最常见的原发肿瘤分别是肺癌22例,肝癌11例。手术可分止痛、稳定瘤骨和肿瘤切除三大类。结果 89例中,77例(86.52%)疼痛缓解或消失。73例获随访(1~9年),1例术后3天死亡,术后3个月内死亡6例,4~6个月死亡7例,7~9个月死亡12例,10~12个月死亡18例,1~2年死亡15例,5例2年以后死亡,至今存活9例,其中1例甲状腺癌脊柱转移者已存活6年。结论 骨转移癌手术的目的是缓解疼痛、改善生存质量和在可能情况下延长生命,而骨转移癌患者的生存时间主要与原发癌的组织学特征有关而与手术本身关系不大。
Surgical Treatment of Metastatic Carcinoma of Bone
FAN Shunwu ,YANG Disheng, TAO Huimin, et al.
The Second Teaching Hospital of Zhejiang Medical University, Hangzhou 310009
【 Abstract 】 Objective To report the clinical experience of surgical treatment of metastatic carcinoma of bone. Methods From February 1988 to March 1997,89 patients with metastatic carcinoma of bones were operated upon. There were 58 males and 31 femals,aged ranged from 10 to 70 years. Seventy-two cases aged between 41 and 70 years. The most frequent sites of bone metastases were the vertebrae (23 cases),femur(22 cases)and pelvis (13 cases).The lungs (22 cases) and liver carcinoma(11 cases) were the most common primary tumors. The operations could be divided into 3 types: 1) for the alleviation of pain, 2) for the restoration of tumor bone stability and 3) for resection of tumor. Results Among 89 cases,77 patients (86.52% ) had good relief of pain. Seventy-three were available for follow-up study. One patients died at the third day after operation ,6 died during 3 months after operation, 7 died between 4 and 6 months,12 died between 7 and 9 months, 18 died between 10 and 12 months , 15 died between 1 and 2 years, 5 died beyond 2 years ......
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