关键词:肺肿瘤/药物疗法;癌,非小细胞肺癌/药物疗法;抗肿瘤药,多剂联用
【摘要】 目的 比较3组不同联合化疗方案对晚期非小细胞肺癌的疗效和毒性。方法 统计分析用IVP(异环磷酰胺、长春地辛、顺铂)方案、MVP(丝裂霉素、长春地辛、顺铂)方案及CAP(环磷酰胺、阿霉素、顺铂)方案治疗的93例晚期非小细胞肺癌病例的临床资料。结果 IVP组有效率为48.4%(15/31),其中完全缓解2例;MVP组有效率为40.0%(12/30),CAP组有效率为28.1%(9/32)。毒副反应主要为骨髓抑制及脱发。结论 以长春地辛为主的IVP及MVP方案为治疗晚期非小细胞肺癌较为有效而安全的化疗方案。
Comparative study of three different chemotherapy protocols foradvanced non-small-cell lung cancer CHEN Longbang, WANG Jinghua, CHU Xiaoyuan, etal. Department of Medical Oncology, Nanjing General Hospital, Nanjing Command of PLA,Nanjing 210002
【Abstract】 Objective To compare the efficacy and toxicityof three different chemotherapy protocols for advanced non-small-cell lung cancer (NSCLC).Methods The clinical data of 93 cases with advanced NSCLC treated with(1) ifosfamide plus vindesine plus cisplatin (IVP, 31 cases), (2) mitomycin C plusvindesine plus cisplatin (MVP, 30 cases), and (3) cyclophosphamide plus adriamycin pluscisplatin (CAP, 32 cases) were analysed. Results The response rate was48.4% in patients treated with IVP ......
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