彭明婷 谷小林 王薇 李雪光 赵声明 陈宝梁 100730 北京，卫生部临床检验中心 中华医学检验杂志 1998 0 0 6


    关键词：国际敏感度指数 凝血活酶 期刊 zhjyyxzz 0 论著 fur -->


    

【摘要 】 目的 标定出凝血活酶参考品(WRP)，为国内凝血活酶产品国际敏感度指数(ISI)的标定提供依据。方法 以凝血活酶国际参考品为标准(IRP)，按照世界卫生组织(WHO)推荐的凝血活酶国际参考品的使用方法进行测定，计算出被标定凝血活酶参考品的ISI值和标定ISI值的变异系数(CV)。结果 标出的凝血活酶参考品的ISI值为1.35，标定ISI值的CV为4.3%。符合WHO的要求(CV≤5%)。结论 用IRP标定的凝血活酶参考品可作为国内凝血活酶试剂ISI值标定的标准。

Detection of theInternational Sensitivity Index for the Working Reference Preparation of thromboplastins Peng Mingting, Gu Xiaolin, Wang Wei, et al. Hematology laboratory, National Center for Clinical Laboratories, Beijing100730

     【 Abstract 】 Objective To assay the InternationalSensitivity Index(ISI) for the Working Reference Preparation(WRP) of thromboplastins. Methods Using the International Reference Preparation(IRP) as the calibrator, according to the method recommended by World Health Organization(WHO) for using the WHO IRP, to do the calibration for the WRP ofthromboplastin against the IRP, calculated the ISI value for the WRP and the coefficientof variation (CV) for the ISI. Results The ISI value of the WRP was 1.35, the CV for the ISI was4.3%, was not up to the standard(less than 5%) recommended by WHO. Conclusion The WRP could be used as thecalibrator for assay the ISI value for thromboplastin reagent.

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