蒋昭实 刘鸿瑞 中国医学科学院 中国协和医科大学 北京协和医院病理科 100730 中华结核和呼吸感染 2000 0 23 1


    关键词：特发性肺纤维化；普通型间质性肺炎；病理学；诊断 期刊 zhjhhhxgr 0 15-18 论 著 fur -->


    

摘 要：目的 探讨普通型间质性肺炎(UIP)与其他类型特发性肺纤维化(IPF)在病理上的鉴别诊断问题。方法 UIP的尸检病例4例，复习其常规染色及组化染色切片。结果 UIP的病理学特征是肺间质的病变轻重不一，新老并存，既有早期的慢性炎症改变，又有进展期的肺泡隔明显纤维化及终末期的蜂窝肺和肌硬化等改变。结论 将UIP与其他类型IPF加以鉴别具有重要的临床意义，因为这些病变的预后和治疗均不同。

Pathologic diagnosis ofusual interstitial pneumonia

JIANG Zhaoshi

    (Pathology Department of PUMC Hospital, PUMC, Beijing 100730, China)

    LIU Hongrui

    (Pathology Department of PUMC Hospital, PUMC, Beijing 100730, China)

Abstract： Objective To discuss pathologicdifferential diagnosis between UIP and the other types of IPF. Method The slides (routine andhistochemical stain) of 4 autopsy cases of UIP were reviewed. Results The most significantcharacteristic of UIP is that the interstitial changes show temporal heterogeneity andvariable distribution. The earlier stage of UIP shows an interstitial infiltrate ofchronic inflammation cells and the progressive stage appears significant interstitialfibrosis. The honeycomb change and muscular cirrhosis are the characteristics of the endstage. Conclusion For clinical purpose, the distinction of UIP and the other types ofIPF is of great significance because of marked differences in the prognosis and therapy.

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