【摘要 】 目的 探讨鲇鱼爱德华杆菌致下呼吸道感染的危险因素和治疗，及该菌近年检出之原因。方法 统计1959～1998年住院患者鲇鱼爱德华杆菌痰培养阳性率，并对其作临床分析。结果1996年以前人工方法检测17500份标本，检出率为0%，1997、1998年用仪器检测1962份标本，检出率为2.3%。两种方法检出率经卡方检验，χ² =420.23，P<0.001。该菌对亚胺硫霉素，头孢噻甲肟，妥布霉素等抗生素有极高敏感度。结论 鲇鱼爱德华杆菌是院内下呼吸道感染的少见条件致病菌，机体抵抗力下降是导致该菌感染的危险因素，检测技术的改进是发现此菌的主要原因。

    

Department of Respiratory Diseases, Xuan Wu Hospital, Capital University of Medical Sciences, Beijing 100053

【Abstract 】 Objective Tostudy the risk factors and treatment of lower respiratory tract infections due to E. ictaluri, and the cause of its improved detection by sputum culture in recent years.Methods To sum up the number of positive cultures and analyze the clinical features ofthe cases with positive sputum culture tested from 1959 to 1998. Results Before 1996,there were no positive cultures (0%) in 17 500 sputum samples using manual techniques, in1997 and 1998 the aggregate positive rate was 2.3% (47/1 962), using SCEPTOR detectinginstrument. On chi square testing of the two results derived from the two methods,P<0.001. On drug sensitivity testing, E. ictaluri was sensitive to imipenem, cefotaximeand tobramycin. Conclusions E. ictaluri is an uncommon opportunistic pathogen of lowerrespiratory tract infections. Lowered body resistance is a risk factor, and improvedtechnology is the principal cause for detection of E. ictaluri infections.

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