马利国 夏震 张丽玲 518020 深圳市人民医院妇产科 中华围产医学杂志 1999 0 0 1


    关键词：阴道病；细菌性；分娩；早产；甲硝唑；红霉素 期刊 zhwcyxzz 0 论 著 fur -->


    

【摘要】 目的 确定在孕20～28周治疗细菌性阴道病(BV)能否降低有早产史孕妇早产发生率。 方法 在产前门诊对有早产史孕妇进行BV筛查，对检出的患者随机分为应用灭滴灵和红霉素治疗及未加治疗组，随诊妊娠结局。 结果 在170例有早产史孕妇中，共检出BV81例、检出率47.6%。41例患者接受灭滴灵及红霉素口服治疗；另40例未予治疗。治疗组孕妇胎膜早破、早产及低出生体重儿发生率分别为24%、20%及17%，低于未治疗组(分别为48%、40%及35%)。 结论 中孕期筛查和口服灭滴灵及红霉素治疗细菌性阴道病可降低有早产史孕妇早产及胎膜早破发生率。

    Reduced Incidence ofPreterm Birth with Metronidazole and Erythromycin in Women with Bacterial Vaginosis

Ma Liguo,Xia Zhen,Zhang Liling. Department ofObstetrics & Gynecology,Shenzhen People's Hospital,Shenzhen 518020

【 Abstract】 Objective To evaluate whether treatment of bacterial vaginosis duringpregnancy with Metronidazole and Erythromycin reduces the incidence of preterm birth. Methods Women seeking prenatalcare at 20～ 28 weeksof gestational age who had bacterial vaginosis were studied.Of 170 women with history ofpreterm birth,81 women,of which 41 were treated,were bacterial vaginosis positive and werefollowed up through delivery. Results The rate of preterm birth (<37 weeks) was 20% for treated patients and 40% for control.The rate ofpremature rupture of membrance was 24.4% for treated patients and 48% for control. Conclusion Treatment of bacterial vaginosis with Metronidazole andErythromycin in women with bacterial vaginosis reduced preterm birth rate and prematurerupture of membrance rate.

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