【摘要】 目的 探讨2E₃ H₃ R₃ Z₃ /4H₃ R₃ (简称含EMB方案)和2S₃ H₃ R₃ Z₃ /4H₃ R₃ (简称含SM方案)在结核病控制工作中的利弊。方法 以河北省石家庄市为研究现场，采用回顾、现况和前瞻性研究方法。结果 含SM和含EMB方案在疗效、复发率和全程督导上无显著性差异；含EMB方案适用性高于含SM方案；SM的副作用明显高于EMB；链霉素皮试阳性率为4.5%；使用SM费用高于使用EMB84%；基层消毒合格率为42.9%，SM注射不安全；患者更愿意接受含EMB方案。结论 含EMB方案比含SM方案更适宜于在结核病控制规划中推行。

    Comparative study on efficacy of regimens includingstreptomycin or ethambutol Li Qunhui, Xiao Chengzhi, Song Wenhu, et al. National Tuberculosis Control Center, Beijing 101149

    【Abstract 】 Objective To evaluate theadvantages and disadvantages of regimens of 2E₃ H₃ R₃ Z₃ /4H₃ R₃ (EMB regimen) and 2S₃ H₃ R₃ Z₃ /4H₃ R₃ (SM regimen) in tuberculosis control program. Method Retrospective,cross-sectional and prospective studies were carried out in Shijiazhuang city, Hebeiprovince from January 1994 to June 1996. Result Therewas no significant difference between the two regimens in efficacy, relapse rate and fullcourse supervision. The EMB regimen was found more applicable than the SM regimen, and theSM regimen caused more side effects than the EMB regimen. Streptomycin skin test had a4.5% positive rate, and using SM costs 84% more than using EMB. One of the drawbacks foundin the SM regimen was that only in 42.9% of the rural sanitation units the disinfectionstandard could be fulfilled, and the patients preferred the EMB regimen to the SM regimen.Conclusion The EMB regimen is more applicable thanthe SM regimen in the tuberculosis control program.

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