李云卿 祁吉 杨子权 张文波 刘继生 郭得安 刘铁 300192 天津市影像医学研究所 天津医科大学第一中心医院 中华放射学杂志 1999 0 33 6


    关键词：体层摄影术；X线计算机； 硬币病变,肺；钙质沉着症；评价研究 期刊 zhfsxzz 0 呼吸系统放射学 fur -->


    

【摘要】 目的 探讨用双能CT检测肺内孤立性结节(SPN)钙质存在的价值，建立一种判断SPN良、恶性的新标准。 方法 用双能(80、140 kVp)CT扫描水模、体模、正常人体、SPN，分析其CT值变化，计算SPN钙盐含量，再用设定密度范围所占区域的面罩样(density mask)后处理显示钙盐形态、分布，判断SPN的良、恶性。 结果 水模、体模、正常人体及SPN中含有高原子序数物质时，低能较高能时CT值升高，且在density mask后处理下显示出钙盐的分布及形态，用此方法诊断SPN良、恶性的敏感性为80%，特异性为80%,χ² =5，P<0.005。 结论 用此方法既能检测出SPN内的钙化，又能显示出钙化形态和分布，对判断SPN的良、恶性有很高的临床价值。

Evaluation of dual-energy computed tomography in detection of calcification in solitary pulmonary nodule

LI Yunqing, QI Ji, YANGZiquan, et al. The First Center Hospital of Tianjin Medical University, Tianjin 300192

【 Abstract 】 Objective To investigate a new method of detecting calcification in solitary pulmonary nodule (SPN) and to build a new standard of distinguishing benign from malignant SPN. Methods Dual-energy CT( 140 kVp、 80 kVp) was performed for water phantom,body phantom, normal volunteers and patients with SPN. The CT number changes were compared and their calcification contents were calculated. The shape and distribution of calcification were displayed by density mask processing and finally diagnosis of benign or malignant SPN was made. Results On low energy CT scan the CT number increased as compared with high energy scan for tissue with high atomic number. The SPN containing calcification also demonstrated increased CT value on low energy scan (sensitivity 80% and specifith 80%;P<0.005). Conclusions Dual-energy CT can demonstrate the calcifications in SPN as well as their appearance and distribution thereby it is a valuable imaging technique for detecting and diagnosing benign or malignant SPN.

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