关键词:腰椎;骨密度;体层摄影术,X线计算机;密度测定法,X线;对比研究
【摘要】 目的 比较腰椎骨密度不同测量方法的异同点,旨在为合理地应用各种腰椎骨密度仪。方法 应用定量CT(简称为QCT)和双能X线骨密度仪(简称为DXA,其中包括椎体正位测量,简称为PA-DXA;侧位全椎体测量,简称为L-DXA;侧位椎体中部测量,简称为ML-DXA) 测量了443例正常人腰椎的骨密度,其中男189例,平均年龄46.9岁;女254例,平均年龄45.7岁。结果 QCT和PA-DXA 的重复性明显优于L-DXA和ML-DXA;年下降率和骨密度线性丢失均以QCT最为明显;无论男女,QCT峰值出现最早,其次是ML-DXA和L-DXA,PA-DXA峰值出现最晚;各种测量方法的相关性与所测的结构是否相似有关。结论 腰椎各种骨密度测量方法各有其特点,各种测量方法仍不能互相取代。
Normal changes i spinal bone mineral density: a comparison between different bone densitometries YU Wei, QIN Mingwei, XING Xiaoping, et al. Department of Radiology, Beijing Union Medical College Hospital, PUMC, Chinese Academy of Medicine Science, Beijing 100730
【Abstract 】 Objective To appreciate use of different spinal bone densitometry, we compared results of spinal bone mineral density (BMD) measured by quantitative CT (QCT) and dual X-ray absorptiometry (DXA) in normal subjects. Methods Four hundred and forty-three healthy subjects (189 males, mean age 46.9 years; 254 females, mean age 45.7 years) were recruited for BMD assessment. BMD was measured by both QCT and DXA, including postero-anterior DXA (PA-DXA), lateral DXA(L-DXA) and midlateral DXA (ML-DXA). Results Reproducibility of QCT and PA-DXA was better than that of L-DXA and ML-DXA. Bone loss measured by QCT were shown to be more rapid in both annual decrement linear regression than that measured by others. For both genders, BMD values peaked earlier when measured by QCT, followed by ML-DXA, L-DXA and PA-DXA. Correlations between different techniques were depended on the structure which the different techniques measured. Conclusions Because of the inherent difference, one method cannot be simply substituted by others.
【 Key words 】 Lumbar vertebrae Bone density Tomography,X-ray computed Densitometry, X-ray Comparative study
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