那淑敏 贾士芳 陈秀珠 陈美玲 郭兴华 还连栋 李金波 李金燕 刘 军 那淑敏 贾士芳 陈秀珠 陈美玲 郭兴华 还连栋 中国科学院微生物研究所 北京 100080；李金波 李金燕 刘 军 黑龙江省泰格药业有限公司 哈尔滨 150078 中国微生态学杂志 1999 0 11 5


    关键词：气相色谱；有机酸；乳酸菌素片 期刊 zgwstxzz 0 论著 fur -->


    

摘 要 气相色谱分析表明，乳酸菌素片生产菌的发酵上清液及药品成品—乳酸菌素粉和乳酸菌素片含有大量乳酸及一定量的丁酸(或异丁酸)、乙酸、正反丁烯二酸、六碳脂肪酸、微量丙酸、琥珀酸及微量抗菌多肽。它们不仅对革兰氏阳性菌，而且对革兰氏阴性菌有不同程度抑制作用。乳酸菌素片医治某些肠胃病的机理正是发酵产生的这些有机酸等代谢产物及发酵后的乳酸菌死菌体及其碎片的作用。

ANALYSIS OF FERMENTATION PRODUCTS PRODUCED

    BY LACTOBACILLUS ACIDOPHILUS

Na Shumin,Jia Shifang,Chen Xiuzhu,et al.

    Institute of Microbiology,Chinese Academy of Sciences,Beijing 100080

    Li Jinbo,Li jinyan,Liu Jun.

    Hei Long Jiang Tiger Pharmaceutical Group Ltd., Harbin 150087

Abstract Fermentation supernatant fluids and Ru Suan Jun Su powder、 tablet contain lactic acid,acetic acid,n/iso butyric acid,maleic acid,fatty acid with hexa-carbon,trace succinic acid,propionic acid by means of gas chromatography and trace antimicrobial peptide.They have broad spectrum of inhibition including many Gram-positive,Gram-negative bacteria especially some pathogenic bacteria,but the levels of inhibition are different.We think that these organic acid and trace antimicrobial peiptide,dead bacteria and debris were able to cure gastroenterits.

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