宋建成 李献云 费立鹏 张培琰 吉中孚 北京回龙观医院100096 中国神经精神疾病杂志 2000 0 26 5


    关键词：精神分裂症；认知症状；情感症状；因子分析 期刊 zgsjjsjbzz 0 257-261 论著与学术交流 fur -->


    

【摘要】 目的 探讨首发精神分裂症患者治疗前存在的独立症状群及其治疗后的变化。方法 对首发精神分裂症患者，在治疗前后分别评定简明精神病评定量表、阴性症状评定量表、汉密尔顿抑郁量表和测查7种认知功能，然后进行因子分析。结果 首发精神分裂症患者的认知症状、阴性症状、情感症状在治疗前、后完全独立，无明显变化；而阳性症状的独立性在治疗前、后则不稳定，因子负荷分别在执行功能、情感症状因子上。结论 在首发精神分裂症患者中情感症状、认知症状是独立存在的，与治疗干预、阴性症状及阳性症状关系不肯定，应重视对两者的评估和治疗。

Factoranalytsis of symptom clusters in first episode schizophrenia patients

Song Jiancheng Li Xiangyun Michael Philips Zhang Peiyan Ji Zhongfu

    (Hui Long Guan Hospital, Hui Long Guan Town,Chang-ping District, Beijing. 100096. Tel:010-62715511-6297)

【Abstract】Objective To identify theindependent symptom clusters of first episode schizophrenic patients prior to treatmentand assess the changes in these clusters after treatment.Methods We conducted a factor analysis of the pre treatment(N=133) and posttreatment (N=144) results of first episode schizophrenia patients administered the Scalefor Assessment of Negative Symptoms, the Hamilton Depression Scale, and seven types ofcognitive tests.Results Negative symptoms, affectivesymptoms, and cognitive symptoms loaded on separate factors that were independent of eachother both before and after treatment, but positive symptoms loaded on several factors andtheir distribution changed with treatment.Conclusions In first episode schizophrenia, affective symptoms and cognitivesymptoms are independent symptom clusters that are unrelated to positive symptoms andnegative symptoms both before and after treatment. The evaluation and treatment of suchsymptoms need to become a routine part of the care of schizophrenic patients.

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