【摘要】 目的 探讨双黄连注射液对乌头碱中毒的治疗作用。 方法 将30例重度乌头碱中毒患者随机分成治疗组和对照组。对照组按常规给予洗胃或催吐、导泻、镇静、输液、抗心律失常、治疗低血压等;治疗组(不洗胃或催吐，亦不导泻)首先给予双黄连注射液滴注，然后输液。 结果 (1)疗效:治疗组疗效明显优于对照组(P<0.01);(2)心律失常恢复时间，治疗组早搏及房颤在10min内全部恢复，窦性心动过缓在12h内恢复，对照组恢复时间则在24h以上(P<0.01)。(3)临床情况:两组临床症状改善时间，治疗组平均(25.15±9.73)min，对照组平均(1764.1±664.35)min;低血压改善时间，治疗组在15min内恢复正常，对照组时间均在27h(1620min)以上(P<0.01)。 结论 双黄连注射液对乌头碱中毒所致心律失常有特效治疗作用。

    【关键词】 乌头碱中毒;双黄连注射液

    Clinical study on shuanghuanglian injections for the treatment of severe aconitine poisoning

    LIU Guo-dong.Department of Emergency，The Chinese Traditional Medicine Hospital，Taoyuan County，Hunan Province，415700，China

    【Abstract】 Objective To investigate the antidotal effect of Shuanghuanglian injections on the patients poisoned by aconitine.Methods Thirty patients were individually randomized into two groups:control group consisted of14pa-tients(11males and3females，age40.8±15.1years)were given routine treatment(gastrolavage，catharsis，transfuse，sedation and treatment with arrhythmic and hypotension etc.).Treatment group consisted of16patients(11males and5females ......