溶血磷脂酸在急性缺血性心脑血管病中预警作用的临床研究
心肌梗死,心肌梗死;心绞痛;脑梗死;溶血磷脂素类血浆,1资料与方法,2结果,3讨论,参考文献
【摘要】目的探讨急性缺血性心脑血管病患者血浆溶血磷脂酸(LPA)的水平。方法入选186例,其中急性缺血性脑卒中(ACI)60例,急性缺血性心血管疾病126例,根据病情将其分为急性心肌梗死(AMI)组66例,不稳定型心绞痛(UAP)组60例,根据抗凝血及抗血小板治疗前UAP为UAP1组,治疗后的UAP为UAP2组,并入选60例健康者作为对照组,分别测定血浆中LPA。结果ACI组、AMI组和UAP1组血浆LPA水平分别为(3.6601±0.6172)μmol/L、(3.8016±0.6286)μmol/L、3.0271±0.7610μmol/L,均显著高于对照组(1.8376±0.6657)μmol/L,P<0.05,其中异常增高率ACI组占60.6%,AMI组占62.8%,UAP1组占47%,UAP2组占13.8%,正常组为4.9%,UAP抗凝及抗血小板治疗后LPA明显降低(2.0049±0.8466)μmol/L。结论血浆中LPA作为体内凝血及血栓形成过程早期释放的分子标记物,在预测急性缺血性心脑血管病中的早期诊断及指导合理应用抗血小板及抗凝药物方面有一定应用价值。关键词:心肌梗死;心绞痛;脑梗死;溶血磷脂素类血浆
Clinical study of plasma lysophosphatidic acid in patients with acute ischemia cardiovascular cerebrovascular diseases
Ding Wei
Heze Municipal Hospital,Shandong 274031.
【Abstract】ObjectiveTo study the level of plasma lysophosphatidic acid (LPA) in patients with acute ischemia cardiovascular cerebrovascular.Methods186 patients were divided into three groups:group ACI in 60 ......
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