【摘要】 目的 评价纳洛酮治疗眩晕症的疗效和有效剂量。 方法 将105例眩晕症患者随机分为常规治疗组、纳洛酮0.4mg组和纳洛酮1.2mg组治疗3～5天。观察各组患者眩晕减轻程度。 结果 纳洛酮0.4mg组3天完全缓解率及总完全缓解率为71.43%(25/35)和91.43%(32/35)，纳洛酮1.2mg组3天完全缓解率及总完全缓解率为77.14%(27/35)和94.29%(33/35)，均明显高于常规治疗组的34.29%(12/35)和71.43%(25/35)，(P<0.01和P<0.05);纳洛酮0.4mg组和纳洛酮1.2mg组疗效差异无统计学意义(P>0.05)。 结论 纳洛酮治疗眩晕症起效快、疗效好，并无明显副作用，每日0.4mg，经济有效，值得推广。

    关键词 纳洛酮 眩晕 β-内啡肽

    Evaluation on naloxone in the treatment of vertigo

    Qin Haijun，Liu Guoping，Shen Junmei，et al.

    Department of Emergency Medicine，Jinshan Hospital Affiliated to Fudan University，Shanghai200540.

    【Abstract】 Objective The purpose of this study is to determine the efficacy and effectual dosage of naloxone for the treatment of vertigo.Methods The105patients with vertigo were randomized into three treatment groups.Treatment group1received normal therapy and treatment group2received0.4mg naloxone while treatment group3re-ceived1.2mg naloxone for three to five days.The mitigatory degree of the patient's vertigo were observed.Results The rate of complete remission for3or5days is71.43%(25/35)and91.43%(32/35)in treatment group2.The rate of complete remission for3or5days is77.14%(27/35)and94.26%(33/35)in treatment group3.It is both higher than the treatment group134.26%(12/35)and71.43%(25/35) ......