【摘要】 目的 观察N 2 O-O 2 静吸复合全麻时急性低通气恢复正常后I-EO 2 和ETCO 2 变化规律的比较。 方法 20例N 2 O-O 2 静吸复合全麻患者，术中机械通气，FiO 2 =0.35。观察由正常V T (10ml/kg)调至4ml/kg后15min和迅速调回至正常后15min内各指标的变化。 结果 低通气后I-EO 2 、ETCO 2 、BP和HR均明显增加。恢复正常通气后HR、BP和ETCO 2 于15min内先后恢复正常，而I-EO 2 仍高出低通气前的17.2%。而且，各观察时点I-EO 2 的变化率均高于ETCO 2 的变化率(P<0.01)。 结论 与ETCO 2 相比，I-EO 2 虽能更早地反映通气量降低，但却不能及时反映通气量的恢复。

    关键词 全身麻醉 通气 吸入气与呼气末氧浓度差 呼气末二氧化碳

    Changes of inspiratory to end-tidal oxygen concentration difference and end-tidal carbon dioxide during acute hypoventilation

    Han Boxiu，Huang Kechang，Wang Xiuying，et al.

    Affiliated Hospital of Weifang Medical College，Weifang261031.

    【Abstract】 Objective To compare the regulation of the changes of inspiratory to end-tidal oxygen concen-tration difference(I-EO 2 )and end-tidal carbon dioxide(ETCO 2 )after the correction of acute hypoventilation during intravenous inhalation anesthesia.Methods Twenty patients underwent N 2 O-O 2 intravenous inhalation anesthesia were received volume-controlled mechanical ventilation with an FiO 2 =0.35.After a period of normal ventilation with V T =10ml/kg ......