【摘要】 目的 探讨低剂量米非司酮配伍双炔失碳酯应用于紧急避孕的效果。 方法 将142例月经规律的合格妇女随机分为2组，观察组(66例)在避孕失败或无保护性性交后72h内开始服用米非司酮10mg+双炔失碳酯5mg，对照组(76例)在避孕失败或无保护性性交后72h内开始服用单剂量米非司酮10mg，观察两组避孕效果、不良反应及月经情况。 结果 采用经典Dixon法计算，观察组避孕有效率为90.6%，对照组避孕有效率为67.4%，观察组诱导出血率低于对照组，但月经变化及不良反应无明显差异。 结论 米非司酮10mg+双炔失碳酯5mg为安全有效、服用简便的紧急避孕方法。

    关键词 米非司酮 双炔失碳酯 紧急避孕

    Mifepristone and C53contraceptive in postcoital contraception

    Luo Xiaohong，Ma Lan，Yang Ying

    Affiliated Hospital，Sichuan Health Administration College，Sichuan610041.

    【Abstract】 Objective To investigate the effect and side-effect of mifepristone in small doses comparing C53contraceptive in postcoital contraception.Methods 142women with normal menstruation were divided into two groups randomly.Observation group(n=66)were given mifepristone10mg and C53contraceptive5mg within72hours after unprotected intercourse or contraception failure.Control group(n=76)were given mifepristone with a sin-gle dose of10mg within72hours after unprotected intercourse or contraception failure.The effect side-effect and menstruation of the two group were compared.Results According to the classic methods of Dixon ......