【摘要】 目的 探讨射线照射诱发胎儿淋巴细胞染色体畸变与新生儿及成年人之间的差别。 方法 选取发育在18、19、20、21、23和36周胎儿，抽取脐带血，新生儿抽取脐带血，成年人及孕妇抽取静脉血， 60 Coγ射线2.0Gy、3.0Gy照射，培养48h，制片，观察淋巴细胞染色体畸变。 结果 辐射诱发胎儿淋巴细胞染色体畸变率:发育20周前显著高于21周后;胎儿淋巴细胞染色体畸变率显著高于新生儿及成年人;孕妇的染色体畸变率高于成年人。 结论 胎儿的辐射敏感性显著高于新生儿及成年人;孕妇的辐射敏感性高于正常成年人。

    关键词 辐射敏感性 染色体畸变 胎儿 成年人 淋巴细胞

    Compare the chromosomal aberrations in lymphocytes of different age groups people by the 60 Coγrays induced

    Du Weixia，Fu Yinghua，Zhao Yun，et al.

    National Institute for Radiological Protection and Nuclear Safety，China CDC，Beijing100088.

    【Abstract】 Objective To study irradiation induced difference age people chromosomal aberrations in lympho-cytes.Methods Cord bloods from the18，19，20，21，23，36weeks fetus and newborns;peripheral blood from adults and pregnant women were to treatment with 60 Coγray under same condition2.0Gy and3.0Gy.The chromosomal aber-rations were analyzed by using conventional method.Results The chromosomal aberrations are higher in20weeks fe-tus than21weeks fetus ......