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编号:10718958
Effect of Traditional Chinese Medicine on Chronic
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    REVIEW

    Effect of Traditional Chinese Medicine on Chronic Prostatitis:

    a Systematic Review of Randomized Controlled Trials*

    Jiaxu Chen??, Lisheng Hu

    Abstract: To systematically evaluate the effectiveness of Chinese herbal drugs on CPT, We searched electronic medical database from China National Knowledge Infrastructure (CNKI), language restriction is Chinese, and date is from 1994-01-01 to 2002-12-31. A total of 108 trials were found. All studies with words like "randomization or quasi-randomization" in their abstracts were included, whether they used blind or not. 19 of these met the entry criteria were downloaded and fully printed. Because All 19 articles were the clinical trials with low quality (Jadad Score<3) in which all the four groups of clinical trials could not provide evidences of EBM A class (including 1a, 1b, 1c level), they could not be used to prove that the treating group is superior to the control group. But the result indicates that Chinese herbal drugs with special efficacy might have a bright medicinal prospect in treating CPT, which deserves a good design of multi-centered, randomized, parallel-controlled and double blinding trials to provide the best EBM evidences (A class A level).

    Key words: randomized controlled trials; prostatitis; Chinese herbal drugs

    Chronic prostatitis (CPT) is a commonly encountered disease with high mobility, which holds 20-30% of the incidence of urinary system and is frequently seen in man of 20~40 years old. It is also a disease with frequent recurrence and a cause of male sterility. Western therapies are not ideal to CPT, while Chinese herbal drugs perform well in treating and relieving this disease.

    1. Oral Chinese herbal therapy

    1.1 Treatment based on Syndrome differentiation

    Seven Syndromes: blood stasis caused by obstruction of dampness, blood stasis due to Qi-stagnation, downward flow of damp-heat, blood stasis caused by Qi-deficiency accompanied by toxins, obstruction of blood stasis due to damp-heat, lingering of evil due to insufficient vital-Qi and the kidney deficiency.

    1.2 Therapy of add-subtract of basic traditional prescriptions (organized by the authors)

    Medicines in treating groups: Daoshihuoxue decoction, Taohechengqi decoction, Sheshecheling decoction, Jingzhuo decoction, Shuangze decoction, method of relieving swelling by treating stranguria; Yishenqingyu decoction, methods like soothing liver to resolve dampness and promoting the blood circulation to resolve blood stasis. Medicines in control groups: only some groups had control medicines like Qianliekang tablet and cinrofloxacin.

    1.3 Special prescription and Herbs (organized by the authors)

    Medicines in treating groups: Zhiqian decoction, Qianlieqing granule, Qianliexiankangfu capsule, Qianliehuichun capsule, Qianliexianyan 3 capsule, Jinpu decoction, Qianliexian pill, Xiansheqianlieshu, Fukeqianjin tablet, Zijin capsule, Qianlie pill, Tonglieshu capsule, Qianlieqing granule compound Zonglvgen powder, Niaodaoqing granule, Feilinqing decoction, Qianlie 1 capsule, Lingyilianqiao decoction and Shireqing oral liquid ......

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