【摘要】 目的 探讨门脉高压性胃病(PHG)患者血清和胃黏膜内一氧化氮(NO)含量的变化。 方法 采用硝酸还原法，将62例PHG患者血清和胃黏膜内NO含量与60例对照组进行比较，并比较轻、重度PHG患者血清和胃黏膜内NO含量变化。 结果 PHG患者血清和胃黏膜内NO含量明显高于对照组，且PHG程度越重，NO含量越高。 结论 NO含量的变化是PHG发病的原因之一。

    【关键词】 门脉高压性胃病;一氧化氮

    Changes of nitric oxide in patients with portal hypertensive gastropathy

    LUMin.

    Department of Gastroenterology Nanxiang Hospital，Shanghai201802，China

    【Abstract】 Objective To investigate the changes of serum and gastric mucosal nitric oxide.Methods Sixty-two PHG patients and sixty normal controls in them serum and gastric mucosal nitric oxide were detected by nitric acid deoxidization method.Results The serum and gastric mucosal concentrations of NO in PHG patients were significant-ly higher than those in the controls.Conclusion The changes of nitric oxide is one of the pathogenesis of PHG.

    【Key words】 portal hypertensive gastropathy(PHG);nitric oxide

    肝硬化患者发生上消化道出血除食管胃底静脉曲张破裂出血外 ......